New Concerns Emerge Around Popular Weight-Loss Drugs
The weight-loss drug Ozempic, hailed for its effectiveness in helping users shed pounds rapidly, is now being associated with a surprising and cosmetic side effect dubbed “Ozempic feet.” Medical experts say the condition results from accelerated fat loss, which not only affects the face and body but now appears to be altering the appearance of users’ feet. As more people turn to GLP-1 receptor agonists like Ozempic and Mounjaro, concerns about their unintended physical effects are becoming more widespread.
“Ozempic feet” refers to the sagging, wrinkled, and aged look that can develop on the top of the feet following substantial fat loss. Unlike the soles, the tops of the feet contain less fat and more delicate skin, making changes more visible. Dr. Barry Weintraub, a board-certified plastic surgeon based in New York, explained that rapid weight loss reduces water retention and subcutaneous fat, revealing structures like tendons and veins, and contributing to a prematurely aged appearance.
This new term joins previously noted cosmetic issues such as “Ozempic face”—sunken cheeks and eyes—and “Ozempic butt,” characterized by a noticeably flattened backside due to lost volume.
Weight-Loss Drugs Celebrity Use Highlights Visible Side Effects
Celebrities who have publicly discussed using weight-loss drugs have sparked fresh speculation about these emerging side effects. Sharon Osbourne, 72, shared a photo with her grandson on Instagram earlier this month that prompted followers to comment on the stark contrast between her smooth face and veiny, aged-looking feet. While Osbourne has acknowledged using and later stopping Ozempic due to excessive weight loss, she has not commented on the specific foot-related effects.
Similarly, Oprah Winfrey, 71, has been open about her use of a GLP-1 drug, though she hasn’t confirmed which one. After losing nearly 50 pounds and stepping down from her role at Weight Watchers, Winfrey described the medication as a “maintenance tool.” At the 2024 NAACP Image Awards, observers noted her feet also appeared looser and more wrinkled, raising speculation that she too may be experiencing “Ozempic feet.”
These instances have fueled broader conversations about how these drugs may visibly impact areas of the body often overlooked in weight-loss journeys.
Growing Popularity, New Treatments, and Caution Ahead
While “Ozempic feet” is still an informal term, it highlights a rising concern tied to the widespread use of GLP-1 medications. In 2024, it was estimated that one in eight Americans had tried drugs like Ozempic or Mounjaro—originally developed for type 2 diabetes but now commonly used off-label for weight loss. As use continues to climb, so does attention to unintended consequences beyond internal health.
To address aesthetic changes, plastic surgeons now offer procedures such as foot lifts and injectable treatments like Skinvive, designed to restore volume and reduce wrinkling. Though still rare, these cosmetic interventions may see greater demand as more users notice visible signs of rapid fat loss.
Healthcare providers are encouraging users to consider both the health benefits and physical side effects of weight-loss medications. While the appeal of fast, effective weight loss is strong, individuals—especially public figures—may have to weigh the psychological and aesthetic impact as well. With the growing use of GLP-1 drugs, awareness around all potential effects, internal and external, is becoming increasingly important.
Also Read :-Study Reveals GLP-1 Drugs Reduce Risks for 42 Health Conditions, Including Heart Attacks and Alzheimer’s
